1) They're usually too big (~30 nm) and thus may not be able to fit in very small morphological regions such as the synaptic cleft, which are usually about 20 nm wide.
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Three problems with quantum dots for in vivo…
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1) They're usually too big (~30 nm) and thus may not be able to fit in very small morphological regions such as the synaptic cleft, which are usually about 20 nm wide.