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Action Potentials for June
1: A new whole animal connectome dropped this month, this time for a three-day-old larva of the annelid worm Platynereis dumerilii. It contains 9162…
Jun 29
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Andy McKenzie
13
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Action Potentials for June
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Searching for memory in the preserved brain
People who are interested in cryonics have a far and away favorite conversation topic, which is why other people aren't interested in pursuing cryonics…
Jun 11
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Andy McKenzie
7
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Searching for memory in the preserved brain
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May 2024
Action Potentials for May
1: Big study describing the connectome of a 1 mm cubic volume of human brain tissue was formally published. The sample was preserved immediately after…
May 26
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Andy McKenzie
9
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Action Potentials for May
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April 2024
Action Potentials for April
1: Study uses unsupervised learning to analyze the dendritic morphologies of over 30,000 excitatory neurons in the mouse visual cortex, built from…
Apr 26
•
Andy McKenzie
5
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Action Potentials for April
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March 2024
Action Potentials for March
1: Big news this month as Johann Danzl’s group at the Institute of Science and Technology Austria released their work on light-microscopy based…
Mar 26
•
Andy McKenzie
7
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Action Potentials for March
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February 2024
Action Potentials for February
1: New study publishes the first large-scale reconstruction of 3D electron microscopy data from the CA3 region of the hippocampus. This is probably my…
Feb 29
•
Andy McKenzie
8
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Action Potentials for February
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January 2024
Action Potentials for January
1: A “representation” refers to the way in which a type of sensory information or an internal state is encoded by the brain. A representation of stored…
Jan 29
•
Andy McKenzie
4
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Action Potentials for January
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Why wasn't preservation with the goal of potential future revival started earlier in history?
John Hunter (1728–1793) did not have an especially promising start to his academic life. He was born the youngest of 10 children to a family living in…
Jan 16
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Andy McKenzie
9
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Why wasn't preservation with the goal of potential future revival started earlier in history?
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December 2023
Action Potentials for December
1: High-pressure freezing is a preservation method that allows relatively larger biospecimens, up to 200 µm thick, to be vitrified. But it requires the…
Dec 27, 2023
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Andy McKenzie
8
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Action Potentials for December
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November 2023
Action Potentials for November
1: Important new study on extrasynaptic neural signaling in C. elegans. In this study, they stimulated each neuron for 30 seconds each, while recording…
Nov 28, 2023
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Andy McKenzie
6
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Action Potentials for November
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October 2023
Action Potentials for October
1: Our new paper on histologic brain age estimation via multiple instance learning dropped this month. Led by the brilliant Gabe Marx. The model…
Oct 21, 2023
•
Andy McKenzie
5
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Action Potentials for October
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September 2023
Action Potentials for September
1: Engram cells are specialized neurons that become active during experiences, undergo chemical and structural changes to store a memory, and can…
Sep 23, 2023
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Andy McKenzie
4
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Action Potentials for September
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